Oleanolic Acid Exerts a Neuroprotective Effect Against Microglial Cell Activation by Modulating Cytokine Release and Antioxidant Defense Systems

Microglia respond to adverse stimuli in order to restore brain homeostasis and, upon activation, they release a number of inflammatory mediators. Chronic microglial overactivation is related to neuroinflammation in Alzheimer’s disease. In this work, we show that oleanolic acid (OA), a natural triter...

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Detalles Bibliográficos
Autores principales: Castellano, José M., Garcia-Rodriguez, Silvia, Espinosa, Juan M., Millan-Linares, María C., Rada, Mirela, Perona, Javier S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921051/
https://www.ncbi.nlm.nih.gov/pubmed/31683841
http://dx.doi.org/10.3390/biom9110683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921051/
https://www.ncbi.nlm.nih.gov/pubmed/31683841
http://dx.doi.org/10.3390/biom9110683

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