Ethanol Impairs NRF2/Antioxidant and Growth Signaling in the Intact Placenta In Vivo and in Human Trophoblasts

NRF2 is a redox-sensitive transcription factor that depending on the duration or magnitude of the stress, either translocates to the nucleus (beneficial) or is degraded in the cytosol (harmful). However, the role of NRF2-based mechanism(s) under ethanol (E)-induced developmental toxicity in the plac...

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Detalles Bibliográficos
Autores principales: Shanmugam, Sambantham, Patel, Dhyanesh, Wolpert, John M., Keshvani, Caezaan, Liu, Xiaobo, Bergeson, Susan E., Kidambi, Srivatsan, Mahimainathan, Lenin, Henderson, George I., Narasimhan, Madhusudhanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921053/
https://www.ncbi.nlm.nih.gov/pubmed/31671572
http://dx.doi.org/10.3390/biom9110669

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