Cargando…

Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung Cells

Stephania tetrandra and other related species of Menispermaceae are the major sources of the bis-benzylisoquinoline alkaloids tetrandrine (TET), fangchinoline (FAN), and cepharanthine (CEP). Although the pharmacological properties of these compounds include anticancer and anti-inflammatory activitie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Dong Eon, Min, Jung Sun, Jang, Min Seong, Lee, Jun Young, Shin, Young Sup, Park, Chul Min, Song, Jong Hwan, Kim, Hyoung Rae, Kim, Seungtaek, Jin, Young-Hee, Kwon, Sunoh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921063/ https://www.ncbi.nlm.nih.gov/pubmed/31690059 http://dx.doi.org/10.3390/biom9110696

Ejemplares similares

Kurarinone Inhibits HCoV-OC43 Infection by Impairing the Virus-Induced Autophagic Flux in MRC-5 Human Lung Cells
por: Min, Jung Sun, et al.
Publicado: (2020)

Auraptene Has Antiviral Activity against Human Coronavirus OC43 in MRC-5 Cells
por: Min, Jung Sun, et al.
Publicado: (2023)

Cardamonin as a p38 MAPK Signaling Pathway Activator Inhibits Human Coronavirus OC43 Infection in Human Lung Cells
por: Jin, Young-Hee, et al.
Publicado: (2023)

Screening antiproliferative drug for breast cancer from bisbenzylisoquinoline alkaloid tetrandrine and fangchinoline derivatives by targeting BLM helicase
por: Zhang, Wangming, et al.
Publicado: (2019)

Benzylisoquinoline Alkaloids Biosynthesis in Sacred Lotus
por: Menéndez-Perdomo, Ivette M., et al.
Publicado: (2018)

Antiviral effects of Korean Red Ginseng on human coronavirus OC43
por: Jeong, Chi Hwan, et al.
Publicado: (2023)

Hairy root induction and benzylisoquinoline alkaloid production in Macleaya cordata
por: Huang, Peng, et al.
Publicado: (2018)

BIAdb: A curated database of benzylisoquinoline alkaloids
por: Singla, Deepak, et al.
Publicado: (2010)

Green Routes for the Production of Enantiopure Benzylisoquinoline Alkaloids
por: Ghirga, Francesca, et al.
Publicado: (2017)

Apoptosis Enhances the Replication of Human Coronavirus OC43
por: Maharjan, Sony, et al.
Publicado: (2021)

Potent antitumor activity of cepharanthine against triple-negative breast cancer spheroids compared with tetrandrine
por: Kiyomi, Anna, et al.
Publicado: (2020)

Improving human coronavirus OC43 (HCoV-OC43) research comparability in studies using HCoV-OC43 as a surrogate for SARS-CoV-2
por: Schirtzinger, Erin E., et al.
Publicado: (2022)

The RNA of human coronavirus OC-43
por: Tannock, Gregory A., et al.
Publicado: (1977)

Role of the phloem in the biochemistry and ecophysiology of benzylisoquinoline alkaloid metabolism
por: Lee, Eun-Jeong, et al.
Publicado: (2013)

Molecular Origins of Functional Diversity in Benzylisoquinoline Alkaloid Methyltransferases
por: Morris, Jeremy S., et al.
Publicado: (2019)

Engineering Saccharomyces cerevisiae to produce plant benzylisoquinoline alkaloids
por: Han, Jianing, et al.
Publicado: (2021)

Modulation of benzylisoquinoline alkaloid biosynthesis by overexpression berberine bridge enzyme in Macleaya cordata
por: Huang, Peng, et al.
Publicado: (2018)

Corrigendum: Molecular Origins of Functional Diversity in Benzylisoquinoline Alkaloid Methyltransferases
por: Morris, Jeremy S., et al.
Publicado: (2019)

Rational Engineering of (S)-Norcoclaurine Synthase for Efficient Benzylisoquinoline Alkaloids Biosynthesis
por: De Sousa, João P. M., et al.
Publicado: (2023)

Visualization and identification of benzylisoquinoline alkaloids in various nelumbo nucifera tissues
por: Hao, Chenyang, et al.
Publicado: (2023)

Biocatalytic Organic Synthesis of Optically Pure (S)-Scoulerine and Berbine and Benzylisoquinoline Alkaloids
por: Schrittwieser, Joerg H., et al.
Publicado: (2011)

Metabolome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants
por: Hagel, Jillian M., et al.
Publicado: (2015)

Transcriptome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants
por: Hagel, Jillian M., et al.
Publicado: (2015)

Identification and Characterization of Genes Involved in Benzylisoquinoline Alkaloid Biosynthesis in Coptis Species
por: He, Si-Mei, et al.
Publicado: (2018)

Investigation of benzylisoquinoline alkaloid biosynthetic pathway and its transcriptional regulation in lotus
por: Deng, Xianbao, et al.
Publicado: (2018)

The chicken gut metagenome and the modulatory effects of plant-derived benzylisoquinoline alkaloids
por: Huang, Peng, et al.
Publicado: (2018)

Benzylisoquinoline Alkaloids from the Stems of Limacia scandens and Their Potential as Autophagy Inhibitors
por: Lee, Hee-Ju, et al.
Publicado: (2022)

De novo biosynthesis of berberine and halogenated benzylisoquinoline alkaloids in Saccharomyces cerevisiae
por: Han, Jianing, et al.
Publicado: (2023)

Structural proteins of human respiratory coronavirus OC43
por: Hogue, Brenda G., et al.
Publicado: (1986)

Optimizing human coronavirus OC43 growth and titration
por: Savoie, Christopher, et al.
Publicado: (2022)

Human Coronavirus OC43 as a Low-Risk Model to Study COVID-19
por: Kim, Mi Il, et al.
Publicado: (2023)

Bis-Benzylisoquinoline Alkaloids Inhibit Porcine Epidemic Diarrhea Virus In Vitro and In Vivo
por: Dong, Shijuan, et al.
Publicado: (2022)

Activation of glial cells by human coronavirus OC43 infection
por: Edwards, Julie A, et al.
Publicado: (2000)

Vacuolating encephalitis in mice infected by human coronavirus OC43
por: Jacomy, Hélène, et al.
Publicado: (2003)

Nonspecific inhibitors of coronavirus OC43 haemagglutination in human sera
por: Hovi, Tapani
Publicado: (1978)

Synthesis and biological evaluation of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4(1H)-one derivatives as potential MERS-CoV inhibitors
por: Yoon, Ji Hye, et al.
Publicado: (2019)

Fangchinoline, a Bisbenzylisoquinoline Alkaloid can Modulate Cytokine-Impelled Apoptosis via the Dual Regulation of NF-κB and AP-1 Pathways
por: Jung, Young Yun, et al.
Publicado: (2019)

Could human coronavirus OC43 have co-evolved with early humans?
por: Brandão, Paulo Eduardo
Publicado: (2018)

Identification of 4-anilino-6-aminoquinazoline derivatives as potential MERS-CoV inhibitors
por: Lee, Jun Young, et al.
Publicado: (2020)

The benzylisoquinoline alkaloids, berberine and coptisine, act against camptothecin-resistant topoisomerase I mutants
por: Inoue, Naomi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3u2gms1js3m3a2n5fn138pa55i