Cargando…
Socio‐behavioural characteristics and HIV: findings from a graphical modelling analysis of 29 sub‐Saharan African countries
INTRODUCTION: Socio‐behavioural factors may contribute to the wide variance in HIV prevalence between and within sub‐Saharan African (SSA) countries. We studied the associations between socio‐behavioural variables potentially related to the risk of acquiring HIV. METHODS: We used Bayesian network mo...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921084/ https://www.ncbi.nlm.nih.gov/pubmed/31854506 http://dx.doi.org/10.1002/jia2.25437 |
_version_ | 1783481082785562624 |
---|---|
author | Baranczuk, Zofia Estill, Janne Blough, Sara Meier, Sonja Merzouki, Aziza Maathuis, Marloes H Keiser, Olivia |
author_facet | Baranczuk, Zofia Estill, Janne Blough, Sara Meier, Sonja Merzouki, Aziza Maathuis, Marloes H Keiser, Olivia |
author_sort | Baranczuk, Zofia |
collection | PubMed |
description | INTRODUCTION: Socio‐behavioural factors may contribute to the wide variance in HIV prevalence between and within sub‐Saharan African (SSA) countries. We studied the associations between socio‐behavioural variables potentially related to the risk of acquiring HIV. METHODS: We used Bayesian network models to study associations between socio‐behavioural variables that may be related to HIV. A Bayesian network consists of nodes representing variables, and edges representing the conditional dependencies between variables. We analysed data from Demographic and Health Surveys conducted in 29 SSA countries between 2010 and 2016. We predefined and dichotomized 12 variables, including factors related to age, literacy, HIV knowledge, HIV testing, domestic violence, sexual activity and women's empowerment. We analysed data on men and women for each country separately and then summarized the results across the countries. We conducted a second analysis including also the individual HIV status in a subset of 23 countries where this information was available. We presented summary graphs showing associations that were present in at least six countries (five in the analysis with HIV status). RESULTS: We analysed data from 190,273 men (range across countries 2295 to 17,359) and 420,198 women (6621 to 38,948). The two variables with the highest total number of edges in the summary graphs were literacy and rural/urban location. Literacy was negatively associated with false beliefs about AIDS and, for women, early sexual initiation, in most countries. Literacy was also positively associated with ever being tested for HIV and the belief that women have the right to ask their husband to use condoms if he has a sexually transmitted infection. Rural location was positively associated with false beliefs about HIV and the belief that beating one's wife is justified, and negatively associated with having been tested for HIV. In the analysis including HIV status, being HIV positive was associated with female‐headed household, older age and rural location among women, and with no variables among men. CONCLUSIONS: Literacy and urbanity were strongly associated with several factors that are important for HIV acquisition. Since literacy is one of the few variables that can be improved by interventions, this makes it a promising intervention target. |
format | Online Article Text |
id | pubmed-6921084 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-69210842019-12-30 Socio‐behavioural characteristics and HIV: findings from a graphical modelling analysis of 29 sub‐Saharan African countries Baranczuk, Zofia Estill, Janne Blough, Sara Meier, Sonja Merzouki, Aziza Maathuis, Marloes H Keiser, Olivia J Int AIDS Soc Research Articles INTRODUCTION: Socio‐behavioural factors may contribute to the wide variance in HIV prevalence between and within sub‐Saharan African (SSA) countries. We studied the associations between socio‐behavioural variables potentially related to the risk of acquiring HIV. METHODS: We used Bayesian network models to study associations between socio‐behavioural variables that may be related to HIV. A Bayesian network consists of nodes representing variables, and edges representing the conditional dependencies between variables. We analysed data from Demographic and Health Surveys conducted in 29 SSA countries between 2010 and 2016. We predefined and dichotomized 12 variables, including factors related to age, literacy, HIV knowledge, HIV testing, domestic violence, sexual activity and women's empowerment. We analysed data on men and women for each country separately and then summarized the results across the countries. We conducted a second analysis including also the individual HIV status in a subset of 23 countries where this information was available. We presented summary graphs showing associations that were present in at least six countries (five in the analysis with HIV status). RESULTS: We analysed data from 190,273 men (range across countries 2295 to 17,359) and 420,198 women (6621 to 38,948). The two variables with the highest total number of edges in the summary graphs were literacy and rural/urban location. Literacy was negatively associated with false beliefs about AIDS and, for women, early sexual initiation, in most countries. Literacy was also positively associated with ever being tested for HIV and the belief that women have the right to ask their husband to use condoms if he has a sexually transmitted infection. Rural location was positively associated with false beliefs about HIV and the belief that beating one's wife is justified, and negatively associated with having been tested for HIV. In the analysis including HIV status, being HIV positive was associated with female‐headed household, older age and rural location among women, and with no variables among men. CONCLUSIONS: Literacy and urbanity were strongly associated with several factors that are important for HIV acquisition. Since literacy is one of the few variables that can be improved by interventions, this makes it a promising intervention target. John Wiley and Sons Inc. 2019-12-19 /pmc/articles/PMC6921084/ /pubmed/31854506 http://dx.doi.org/10.1002/jia2.25437 Text en © 2019 The Authors. Journal of the International AIDS Society published by John Wiley & Sons Ltd on behalf of the International AIDS Society. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Baranczuk, Zofia Estill, Janne Blough, Sara Meier, Sonja Merzouki, Aziza Maathuis, Marloes H Keiser, Olivia Socio‐behavioural characteristics and HIV: findings from a graphical modelling analysis of 29 sub‐Saharan African countries |
title | Socio‐behavioural characteristics and HIV: findings from a graphical modelling analysis of 29 sub‐Saharan African countries |
title_full | Socio‐behavioural characteristics and HIV: findings from a graphical modelling analysis of 29 sub‐Saharan African countries |
title_fullStr | Socio‐behavioural characteristics and HIV: findings from a graphical modelling analysis of 29 sub‐Saharan African countries |
title_full_unstemmed | Socio‐behavioural characteristics and HIV: findings from a graphical modelling analysis of 29 sub‐Saharan African countries |
title_short | Socio‐behavioural characteristics and HIV: findings from a graphical modelling analysis of 29 sub‐Saharan African countries |
title_sort | socio‐behavioural characteristics and hiv: findings from a graphical modelling analysis of 29 sub‐saharan african countries |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921084/ https://www.ncbi.nlm.nih.gov/pubmed/31854506 http://dx.doi.org/10.1002/jia2.25437 |
work_keys_str_mv | AT baranczukzofia sociobehaviouralcharacteristicsandhivfindingsfromagraphicalmodellinganalysisof29subsaharanafricancountries AT estilljanne sociobehaviouralcharacteristicsandhivfindingsfromagraphicalmodellinganalysisof29subsaharanafricancountries AT bloughsara sociobehaviouralcharacteristicsandhivfindingsfromagraphicalmodellinganalysisof29subsaharanafricancountries AT meiersonja sociobehaviouralcharacteristicsandhivfindingsfromagraphicalmodellinganalysisof29subsaharanafricancountries AT merzoukiaziza sociobehaviouralcharacteristicsandhivfindingsfromagraphicalmodellinganalysisof29subsaharanafricancountries AT maathuismarloesh sociobehaviouralcharacteristicsandhivfindingsfromagraphicalmodellinganalysisof29subsaharanafricancountries AT keiserolivia sociobehaviouralcharacteristicsandhivfindingsfromagraphicalmodellinganalysisof29subsaharanafricancountries |