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Synthesis, characterization and evaluation of deacetylated xanthan derivatives as new excipients in the formulation of chitosan-based polyelectrolytes for the sustained release of tramadol

This paper addressed the application of deacetylated xanthan (XGDS) and chitosan (CTS) as a mixture blend forming hydrophilic matrices for Tramadol (TD) sustained release tablets. XGDSs derivatives were obtained by alkaline treatment of xanthan gum (XG) with various degrees of deacetylation (DD). Th...

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Detalles Bibliográficos
Autores principales:	Boudoukhani, Meriem, Yahoum, Madiha M., Lefnaoui, Sonia, Moulai-Mostefa, Nadji, Banhobre, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921171/ https://www.ncbi.nlm.nih.gov/pubmed/31885472 http://dx.doi.org/10.1016/j.jsps.2019.09.009

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