Design, synthesis, and evaluation of novel 2-substituted 1,4-benzenediol library as antimicrobial agents against clinically relevant pathogens

Development of new antimicrobial agents, capable of combating resistant and multidrug-resistant fungal and bacterial clinical strains, is necessary. This study presents the synthesis and antimicrobial screening of 42 2-substituted-1,4-benzenediols, being 10 novel compounds. In total, 23 compounds sh...

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Detalles Bibliográficos
Autores principales: Dalla Lana, Daiane Flores, Batista, Bruna Gerardon, da Rosa Machado, Gabriella, Teixeira, Mário Lettieri, de Oliveira, Luís Flávio Souza, Machado, Michel Mansur, de Andrade, Saulo Fernandes, Lopes, William, Vainstein, Marilene Henning, de Abreu Lima, Alejandro Peixoto, Pandolfi, Enrique, Silva, Edilma Elayne, Fuentefria, Alexandre Meneghello, Silveira, Gustavo Pozza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921195/
https://www.ncbi.nlm.nih.gov/pubmed/31885466
http://dx.doi.org/10.1016/j.jsps.2019.09.003

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