Synthesis of 1-Azaspiro[4.4]nonane Derivatives Enabled by Domino Radical Bicyclization Involving Formation and Capture of Alkoxyaminyl Radicals

[Image: see text] The application of a domino radical bicyclization for the synthesis of compounds containing the 1-azaspiro[4.4]nonane skeleton in 11–67% yields as a mixture of diastereomers is described (trans configuration preference). This process involved formation and capture of alkoxyaminyl r...

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Detalles Bibliográficos
Autores principales: Guerrero-Caicedo, Alejandro, Soto-Martínez, Diana M., Osorio, David A., Novoa, Muskendol, Loaiza, Alix E., Jaramillo-Gómez, Luz M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921261/
https://www.ncbi.nlm.nih.gov/pubmed/31867503
http://dx.doi.org/10.1021/acsomega.9b02515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921261/
https://www.ncbi.nlm.nih.gov/pubmed/31867503
http://dx.doi.org/10.1021/acsomega.9b02515

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