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Ligustilide protects PC12 cells from oxygen-glucose deprivation/reoxygenation-induced apoptosis via the LKB1-AMPK-mTOR signaling pathway

Autophagy has been shown to have a protective effect against brain damage. Ligustilide (LIG) is a bioactive substance isolated from Ligusticum chuanxiong, a traditional Chinese medicine. LIG has a neuroprotective effect; however, it is unclear whether this neuroprotective effect involves autophagy....

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Detalles Bibliográficos
Autores principales: Zhao, Dan-Yang, Yu, Dong-Dong, Ren, Li, Bi, Guo-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921349/
https://www.ncbi.nlm.nih.gov/pubmed/31571659
http://dx.doi.org/10.4103/1673-5374.266059