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Abnormal regulation of glucagon secretion by human islet alpha cells in the absence of beta cells
BACKGROUND: The understanding of the regulation of glucagon secretion by pancreatic islet α-cells remains elusive. We aimed to develop an in vitro model for investigating the function of human α-cells under direct influence of glucose and other potential regulators. METHODS: Highly purified human α-...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921359/ https://www.ncbi.nlm.nih.gov/pubmed/31780397 http://dx.doi.org/10.1016/j.ebiom.2019.11.018 |