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Sprouty4 correlates with favorable prognosis in perihilar cholangiocarcinoma by blocking the FGFR-ERK signaling pathway and arresting the cell cycle

BACKGROUND: Perihilar cholangiocarcinoma (PHCC) is the most common subtype of cholangiocarcinoma(CCA). We previously investigated the expression pattern of Sprouty(SPRY) in intrahepatic cholangiocarcinoma(ICC), but the expression and clinical significance of SPRY family members in PHCC are still unk...

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Detalles Bibliográficos
Autores principales: Qiu, Bo, Chen, Tianli, Sun, Rongqi, Liu, Zengli, Zhang, Xiaoming, Li, Zhipeng, Xu, Yunfei, Zhang, Zongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921364/
https://www.ncbi.nlm.nih.gov/pubmed/31761616
http://dx.doi.org/10.1016/j.ebiom.2019.11.021