In vitro toxic evaluation of two gliptins and their main impurities of synthesis

BACKGROUND: The presence of impurities in some drugs may compromise the safety and efficacy of the patient’s treatment. Therefore, establishing of the biological safety of the impurities is essential. Diabetic patients are predisposed to tissue damage due to an increased oxidative stress process; an...

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Detalles Bibliográficos
Autores principales: Giordani, Camila F. A., Campanharo, Sarah, Wingert, Nathalie R., Bueno, Lívia M., Manoel, Joanna W., Costa, Barbara, Cattani, Shanda, Arbo, Marcelo Dutra, Garcia, Solange Cristina, Garcia, Cássia Virginia, Volpato, Nádia Maria, Schapoval, Elfrides Eva Scherman, Steppe, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921383/
https://www.ncbi.nlm.nih.gov/pubmed/31852534
http://dx.doi.org/10.1186/s40360-019-0354-2

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