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Generating microglia from human pluripotent stem cells: novel in vitro models for the study of neurodegeneration

Microglia play an essential role for central nervous system (CNS) development and homeostasis and have been implicated in the onset, progression, and clearance of numerous diseases affecting the CNS. Previous in vitro research on human microglia was restricted to post-mortem brain tissue-derived mic...

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Detalles Bibliográficos
Autores principales: Speicher, Anna M., Wiendl, Heinz, Meuth, Sven G., Pawlowski, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921408/
https://www.ncbi.nlm.nih.gov/pubmed/31856864
http://dx.doi.org/10.1186/s13024-019-0347-z