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Generating microglia from human pluripotent stem cells: novel in vitro models for the study of neurodegeneration
Microglia play an essential role for central nervous system (CNS) development and homeostasis and have been implicated in the onset, progression, and clearance of numerous diseases affecting the CNS. Previous in vitro research on human microglia was restricted to post-mortem brain tissue-derived mic...
Autores principales: | Speicher, Anna M., Wiendl, Heinz, Meuth, Sven G., Pawlowski, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921408/ https://www.ncbi.nlm.nih.gov/pubmed/31856864 http://dx.doi.org/10.1186/s13024-019-0347-z |
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