Reduced H3K27me3 leads to abnormal Hox gene expression in neural tube defects

BACKGROUND: Neural tube defects (NTDs) are severe, common birth defects that result from failure of normal neural tube closure during early embryogenesis. Accumulating strong evidence indicates that genetic factors contribute to NTDs etiology, among them, HOX genes play a key role in neural tube clo...

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Detalles Bibliográficos
Autores principales: Yu, Juan, Wang, Lei, Pei, Pei, Li, Xue, Wu, Jianxin, Qiu, Zhiyong, Zhang, Juan, Ao, Ruifang, Wang, Shan, Zhang, Ting, Xie, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921514/
https://www.ncbi.nlm.nih.gov/pubmed/31856916
http://dx.doi.org/10.1186/s13072-019-0318-1

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