Association between component-resolved diagnosis of house dust mite and efficacy of allergen immunotherapy in allergic rhinitis patients

Data regarding clinical relevance of house dust mite (HDM) components over allergen immunotherapy (AIT) for allergic rhinitis (AR) are lacking. 18 adult AR patients receiving HDM-AIT for 52 weeks were followed up to assess serum levels of sIgE and sIgG4 to HDM components. The study showed that Der p...

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Autores principales: Huang, Yanran, Wang, Chengshuo, Lin, Xi, Lou, Hongfei, Cao, Feifei, Li, Wenhan, Zhang, Yuan, Zhang, Luo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921530/
https://www.ncbi.nlm.nih.gov/pubmed/31890153
http://dx.doi.org/10.1186/s13601-019-0305-4
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author Huang, Yanran
Wang, Chengshuo
Lin, Xi
Lou, Hongfei
Cao, Feifei
Li, Wenhan
Zhang, Yuan
Zhang, Luo
author_facet Huang, Yanran
Wang, Chengshuo
Lin, Xi
Lou, Hongfei
Cao, Feifei
Li, Wenhan
Zhang, Yuan
Zhang, Luo
author_sort Huang, Yanran
collection PubMed
description Data regarding clinical relevance of house dust mite (HDM) components over allergen immunotherapy (AIT) for allergic rhinitis (AR) are lacking. 18 adult AR patients receiving HDM-AIT for 52 weeks were followed up to assess serum levels of sIgE and sIgG4 to HDM components. The study showed that Der p1, p2, p23, Der f1 and f2, are important sensitizing components of HDM, of which Der p1 appears to be the most clinically relevant allergenic component for effective AIT.
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spelling pubmed-69215302019-12-30 Association between component-resolved diagnosis of house dust mite and efficacy of allergen immunotherapy in allergic rhinitis patients Huang, Yanran Wang, Chengshuo Lin, Xi Lou, Hongfei Cao, Feifei Li, Wenhan Zhang, Yuan Zhang, Luo Clin Transl Allergy Letter to the Editor Data regarding clinical relevance of house dust mite (HDM) components over allergen immunotherapy (AIT) for allergic rhinitis (AR) are lacking. 18 adult AR patients receiving HDM-AIT for 52 weeks were followed up to assess serum levels of sIgE and sIgG4 to HDM components. The study showed that Der p1, p2, p23, Der f1 and f2, are important sensitizing components of HDM, of which Der p1 appears to be the most clinically relevant allergenic component for effective AIT. BioMed Central 2019-12-19 /pmc/articles/PMC6921530/ /pubmed/31890153 http://dx.doi.org/10.1186/s13601-019-0305-4 Text en © The Author(s) 2019 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Letter to the Editor
Huang, Yanran
Wang, Chengshuo
Lin, Xi
Lou, Hongfei
Cao, Feifei
Li, Wenhan
Zhang, Yuan
Zhang, Luo
Association between component-resolved diagnosis of house dust mite and efficacy of allergen immunotherapy in allergic rhinitis patients
title Association between component-resolved diagnosis of house dust mite and efficacy of allergen immunotherapy in allergic rhinitis patients
title_full Association between component-resolved diagnosis of house dust mite and efficacy of allergen immunotherapy in allergic rhinitis patients
title_fullStr Association between component-resolved diagnosis of house dust mite and efficacy of allergen immunotherapy in allergic rhinitis patients
title_full_unstemmed Association between component-resolved diagnosis of house dust mite and efficacy of allergen immunotherapy in allergic rhinitis patients
title_short Association between component-resolved diagnosis of house dust mite and efficacy of allergen immunotherapy in allergic rhinitis patients
title_sort association between component-resolved diagnosis of house dust mite and efficacy of allergen immunotherapy in allergic rhinitis patients
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921530/
https://www.ncbi.nlm.nih.gov/pubmed/31890153
http://dx.doi.org/10.1186/s13601-019-0305-4
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