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KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3
BACKGROUND: N6-methyladenosine (m6A) modification, the most abundant internal methylation of eukaryotic RNA transcripts, is critically implicated in RNA processing. As the largest known component in the m6A methyltransferase complex, KIAA1429 plays a vital role in m6A methylation. However, its funct...
Autores principales: | Lan, Tian, Li, Hui, Zhang, Delin, Xu, Lin, Liu, Hailing, Hao, Xiangyong, Yan, Xiaokai, Liao, Haotian, Chen, Xiangzheng, Xie, Kunlin, Li, Jiaxin, Liao, Mingheng, Huang, Jiwei, Yuan, Kefei, Zeng, Yong, Wu, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921542/ https://www.ncbi.nlm.nih.gov/pubmed/31856849 http://dx.doi.org/10.1186/s12943-019-1106-z |
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