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Up-regulation of IGF2BP2 by multiple mechanisms in pancreatic cancer promotes cancer proliferation by activating the PI3K/Akt signaling pathway

BACKGROUND: The survival of pancreatic cancer patients remains poor. However, the underlying molecular mechanism and new therapeutic target of pancreatic cancer are still needed to be found. Many studies have shown that the IGF2 mRNA-binding protein 2 (IGF2BP2) plays oncogenic roles in cancers. Howe...

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Detalles Bibliográficos
Autores principales:	Xu, Xiaodong, Yu, Yan, Zong, Ke, Lv, Pengwei, Gu, Yuantin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921559/ https://www.ncbi.nlm.nih.gov/pubmed/31852504 http://dx.doi.org/10.1186/s13046-019-1470-y

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