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Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1α/β-mediated adaptive stress response pathway in skeletal muscle cells

BACKGROUND: While the role of Polycomb group protein-mediated “cell memory” is well established in developmental contexts, little is known about their role in adult tissues and in particular in post-mitotic cells. Emerging evidence assigns a pivotal role in cell plasticity and adaptation. PRC2-Ezh1α...

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Detalles Bibliográficos
Autores principales: Liu, Peng, Shuaib, Muhammad, Zhang, Huoming, Nadeef, Seba, Orlando, Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921592/
https://www.ncbi.nlm.nih.gov/pubmed/31856907
http://dx.doi.org/10.1186/s13072-019-0322-5