Automated minute scale RNA-seq of pluripotent stem cell differentiation reveals early divergence of human and mouse gene expression kinetics

Pluripotent stem cells retain the developmental timing of their species of origin in vitro, an observation that suggests the existence of a cell-intrinsic developmental clock, yet the nature and machinery of the clock remain a mystery. We hypothesize that one possible component may lie in species-sp...

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Detalles Bibliográficos
Autores principales: Barry, Christopher, Schmitz, Matthew T., Argus, Cara, Bolin, Jennifer M., Probasco, Mitchell D., Leng, Ning, Duffin, Bret M., Steill, John, Swanson, Scott, McIntosh, Brian E., Stewart, Ron, Kendziorski, Christina, Thomson, James A., Bacher, Rhonda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922475/
https://www.ncbi.nlm.nih.gov/pubmed/31815944
http://dx.doi.org/10.1371/journal.pcbi.1007543

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