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Physical decoupling of XylS/Pm regulatory elements and conditional proteolysis enable precise control of gene expression in Pseudomonas putida

Most of the gene expression systems available for Gram‐negative bacteria are afflicted by relatively high levels of basal (i.e. leaky) expression of the target gene(s). This occurrence affects the system dynamics, ultimately reducing the output and productivity of engineered pathways and synthetic c...

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Detalles Bibliográficos
Autores principales: Volke, Daniel C., Turlin, Justine, Mol, Viviënne, Nikel, Pablo I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922516/
https://www.ncbi.nlm.nih.gov/pubmed/30864281
http://dx.doi.org/10.1111/1751-7915.13383