Cargando…
Cas9-based enrichment and single-molecule sequencing for precise characterization of genomic duplications
The widespread use of genome-wide diagnostic screening methods has greatly increased the frequency with which incidental (but possibly pathogenic) copy number changes affecting single genes are detected. These findings require validation to allow appropriate clinical management. Deletion variants ca...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923135/ https://www.ncbi.nlm.nih.gov/pubmed/31273287 http://dx.doi.org/10.1038/s41374-019-0283-0 |