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Functional consequences of mitochondrial mismatch in reconstituted embryos and offspring

Animal cloning technology has been developed to produce progenies genetically identical to a given donor cell. However, in nuclear transfer protocols, the recipient oocytes contribute a heritable mitochondrial genomic (mtDNA) background to the progeny. Additionally, a small amount of donor cell-deri...

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Detalles Bibliográficos
Autor principal: TAKEDA, Kumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923153/
https://www.ncbi.nlm.nih.gov/pubmed/31462597
http://dx.doi.org/10.1262/jrd.2019-089