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Heme-Oxygenase-1 Is Decreased in Circulating Monocytes and Is Associated With Impaired Phagocytosis and ROS Production in Lupus Nephritis

Lupus nephritis (LN) is one of the most serious manifestations of systemic lupus erythematosus (SLE). Based on studies showing the potential role of heme oxygenase-1 (HO-1), an enzyme that catalyzes the degradation of heme and has anti-inflammatory properties in SLE development, we decided to explor...

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Detalles Bibliográficos
Autores principales: Cuitino, Loreto, Obreque, Javiera, Gajardo-Meneses, Patricia, Villarroel, Alejandra, Crisóstomo, Natalia, San Francisco, Ignacio F., Valenzuela, Rodrigo A., Méndez, Gonzalo P., Llanos, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923251/
https://www.ncbi.nlm.nih.gov/pubmed/31921135
http://dx.doi.org/10.3389/fimmu.2019.02868