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Cultivated Escherichia coli diversity in intestinal microbiota of Crohn's disease patients and healthy individuals: Whole genome data
Dysbiosis of the gut microbiota in inflammatory bowel disease (IBD) patients is of great interest. It has been reported that Crohn's disease (CD) is associated with a general decrease in microbial diversity [1]. Altered microbial composition and function in CD results in imbalance in host-bacte...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923290/ https://www.ncbi.nlm.nih.gov/pubmed/31886370 http://dx.doi.org/10.1016/j.dib.2019.104948 |
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author | Siniagina, Maria Markelova, Maria Laikov, Alexander Boulygina, Eugenia Khusnutdinova, Dilyara Kharchenko, Anastasia Misbakhova, Albina Grigoryeva, Tatiana |
author_facet | Siniagina, Maria Markelova, Maria Laikov, Alexander Boulygina, Eugenia Khusnutdinova, Dilyara Kharchenko, Anastasia Misbakhova, Albina Grigoryeva, Tatiana |
author_sort | Siniagina, Maria |
collection | PubMed |
description | Dysbiosis of the gut microbiota in inflammatory bowel disease (IBD) patients is of great interest. It has been reported that Crohn's disease (CD) is associated with a general decrease in microbial diversity [1]. Altered microbial composition and function in CD results in imbalance in host-bacteria interaction and increased immune stimulation [2]. It is shown that microbiota in CD is characterized by increased proportion of E. coli in human gut in contrast to healthy individuals [3]. However, the overall qualitative and quantitative diversity of E. coli strains in CD is not fully understood. Here, we present a dataset of whole-genome sequences of E. coli's. |
format | Online Article Text |
id | pubmed-6923290 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-69232902019-12-27 Cultivated Escherichia coli diversity in intestinal microbiota of Crohn's disease patients and healthy individuals: Whole genome data Siniagina, Maria Markelova, Maria Laikov, Alexander Boulygina, Eugenia Khusnutdinova, Dilyara Kharchenko, Anastasia Misbakhova, Albina Grigoryeva, Tatiana Data Brief Immunology and Microbiology Dysbiosis of the gut microbiota in inflammatory bowel disease (IBD) patients is of great interest. It has been reported that Crohn's disease (CD) is associated with a general decrease in microbial diversity [1]. Altered microbial composition and function in CD results in imbalance in host-bacteria interaction and increased immune stimulation [2]. It is shown that microbiota in CD is characterized by increased proportion of E. coli in human gut in contrast to healthy individuals [3]. However, the overall qualitative and quantitative diversity of E. coli strains in CD is not fully understood. Here, we present a dataset of whole-genome sequences of E. coli's. Elsevier 2019-12-05 /pmc/articles/PMC6923290/ /pubmed/31886370 http://dx.doi.org/10.1016/j.dib.2019.104948 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Immunology and Microbiology Siniagina, Maria Markelova, Maria Laikov, Alexander Boulygina, Eugenia Khusnutdinova, Dilyara Kharchenko, Anastasia Misbakhova, Albina Grigoryeva, Tatiana Cultivated Escherichia coli diversity in intestinal microbiota of Crohn's disease patients and healthy individuals: Whole genome data |
title | Cultivated Escherichia coli diversity in intestinal microbiota of Crohn's disease patients and healthy individuals: Whole genome data |
title_full | Cultivated Escherichia coli diversity in intestinal microbiota of Crohn's disease patients and healthy individuals: Whole genome data |
title_fullStr | Cultivated Escherichia coli diversity in intestinal microbiota of Crohn's disease patients and healthy individuals: Whole genome data |
title_full_unstemmed | Cultivated Escherichia coli diversity in intestinal microbiota of Crohn's disease patients and healthy individuals: Whole genome data |
title_short | Cultivated Escherichia coli diversity in intestinal microbiota of Crohn's disease patients and healthy individuals: Whole genome data |
title_sort | cultivated escherichia coli diversity in intestinal microbiota of crohn's disease patients and healthy individuals: whole genome data |
topic | Immunology and Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923290/ https://www.ncbi.nlm.nih.gov/pubmed/31886370 http://dx.doi.org/10.1016/j.dib.2019.104948 |
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