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Sensitivity of transcription factors to DNA methylation

Dynamic binding of transcription factors (TFs) to regulatory elements controls transcriptional states throughout organism development. Epigenetics modifications, such as DNA methylation mostly within cytosine-guanine dinucleotides (CpGs), have the potential to modulate TF binding to DNA. Although DN...

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Detalles Bibliográficos
Autores principales: Héberlé, Éléa, Bardet, Anaïs Flore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923324/
https://www.ncbi.nlm.nih.gov/pubmed/31755929
http://dx.doi.org/10.1042/EBC20190033