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The application of Box-Behnken-Design in the optimization of HPLC separation of fluoroquinolones

Box-Behnken Design is a useful tool for the optimization of the chromatographic analysis. The goal of this study was to select the most significant factors that influenced the following parameters of the chromatographic separation: retention time, relative retention time, symmetry of the peaks, tail...

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Detalles Bibliográficos
Autores principales:	Czyrski, Andrzej, Sznura, Justyna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923357/ https://www.ncbi.nlm.nih.gov/pubmed/31857613 http://dx.doi.org/10.1038/s41598-019-55761-z

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