Cargando…
Multi-parameter immune profiling of peripheral blood mononuclear cells by multiplexed single-cell mass cytometry in patients with early multiple sclerosis
Multiple sclerosis (MS) is an inflammatory demyelinating and neurodegenerative disease of the central nervous system (CNS). Studies in rodent models demonstrated an association of CNS-infiltrating monocyte-derived macrophages with disease severity. However, little is known about humans. Here, we per...
Autores principales: | Böttcher, Chotima, Fernández-Zapata, Camila, Schlickeiser, Stephan, Kunkel, Desiree, Schulz, Axel R., Mei, Henrik E., Weidinger, Carl, Gieß, René M., Asseyer, Susanna, Siegmund, Britta, Paul, Friedemann, Ruprecht, Klemens, Priller, Josef |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923404/ https://www.ncbi.nlm.nih.gov/pubmed/31857644 http://dx.doi.org/10.1038/s41598-019-55852-x |
Ejemplares similares
-
Single-cell mass cytometry of microglia in major depressive disorder reveals a non-inflammatory phenotype with increased homeostatic marker expression
por: Böttcher, Chotima, et al.
Publicado: (2020) -
The use and limitations of single‐cell mass cytometry for studying human microglia function
por: Fernández‐Zapata, Camila, et al.
Publicado: (2020) -
Single-cell mass cytometry reveals complex myeloid cell composition in active lesions of progressive multiple sclerosis
por: Böttcher, Chotima, et al.
Publicado: (2020) -
1,2-(13)C(2)-Glucose Tracing Approach to Assess Metabolic Alterations of Human Monocytes under Neuroinflammatory Conditions
por: Giacomello, Ginevra, et al.
Publicado: (2023) -
Differential compartmentalization of myeloid cell phenotypes and responses towards the CNS in Alzheimer’s disease
por: Fernández Zapata, Camila, et al.
Publicado: (2022)