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An ultrasensitive fiveplex activity assay for cellular kinases
Protein kinases are enzymes whose abundance, protein-protein interactions, and posttranslational modifications together determine net signaling activity in cells. Large-scale data on cellular kinase activity are limited, because existing assays are cumbersome, poorly sensitive, low throughput, and r...
Autores principales: | Smolko, Christian M., Janes, Kevin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923413/ https://www.ncbi.nlm.nih.gov/pubmed/31857650 http://dx.doi.org/10.1038/s41598-019-55998-8 |
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