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Identification of a novel cholesterol-lowering dipeptide, phenylalanine-proline (FP), and its down-regulation of intestinal ABCA1 in hypercholesterolemic rats and Caco-2 cells

There has been no report about in vivo active cholesterol-lowering dipeptide in any protein origin, despite their potential health benefits. Cattle heart protein hydrolysate ultra-filtrate (HPHU, molecular weight < ca. 1,000 Da peptide mixture) exhibits cholesterol-lowering activity in hyperchole...

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Detalles Bibliográficos
Autores principales:	Banno, Arata, Wang, Jilite, Okada, Kenji, Mori, Ryosuke, Mijiti, Maihemuti, Nagaoka, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923426/ https://www.ncbi.nlm.nih.gov/pubmed/31857643 http://dx.doi.org/10.1038/s41598-019-56031-8

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