A Flow Induced Autoimmune Response and Accelerated Senescence of Red Blood Cells in Cardiovascular Devices

Red blood cells (RBCs) passing through heart pumps, prosthetic heart valves and other cardiovascular devices undergo early senescence attributed to non-physiologic forces. We hypothesized that mechanical trauma accelerates aging by deformation of membrane proteins to cause binding of naturally occur...

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Detalles Bibliográficos
Autores principales: Buerck, James P., Burke, Dustin K., Schmidtke, David W., Snyder, Trevor A., Papavassiliou, Dimitrios, O’Rear, Edgar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923429/
https://www.ncbi.nlm.nih.gov/pubmed/31857631
http://dx.doi.org/10.1038/s41598-019-55924-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923429/
https://www.ncbi.nlm.nih.gov/pubmed/31857631
http://dx.doi.org/10.1038/s41598-019-55924-y

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