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Edematous severe acute malnutrition is characterized by hypomethylation of DNA
Edematous severe acute childhood malnutrition (edematous SAM or ESAM), which includes kwashiorkor, presents with more overt multi-organ dysfunction than non-edematous SAM (NESAM). Reduced concentrations and methyl-flux of methionine in 1-carbon metabolism have been reported in acute, but not recover...
Autores principales: | Schulze, Katharina V., Swaminathan, Shanker, Howell, Sharon, Jajoo, Aarti, Lie, Natasha C., Brown, Orgen, Sadat, Roa, Hall, Nancy, Zhao, Liang, Marshall, Kwesi, May, Thaddaeus, Reid, Marvin E., Taylor-Bryan, Carolyn, Wang, Xueqing, Belmont, John W., Guan, Yongtao, Manary, Mark J., Trehan, Indi, McKenzie, Colin A., Hanchard, Neil A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923441/ https://www.ncbi.nlm.nih.gov/pubmed/31857576 http://dx.doi.org/10.1038/s41467-019-13433-6 |
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