Edematous severe acute malnutrition is characterized by hypomethylation of DNA

Edematous severe acute childhood malnutrition (edematous SAM or ESAM), which includes kwashiorkor, presents with more overt multi-organ dysfunction than non-edematous SAM (NESAM). Reduced concentrations and methyl-flux of methionine in 1-carbon metabolism have been reported in acute, but not recover...

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Detalles Bibliográficos
Autores principales: Schulze, Katharina V., Swaminathan, Shanker, Howell, Sharon, Jajoo, Aarti, Lie, Natasha C., Brown, Orgen, Sadat, Roa, Hall, Nancy, Zhao, Liang, Marshall, Kwesi, May, Thaddaeus, Reid, Marvin E., Taylor-Bryan, Carolyn, Wang, Xueqing, Belmont, John W., Guan, Yongtao, Manary, Mark J., Trehan, Indi, McKenzie, Colin A., Hanchard, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923441/
https://www.ncbi.nlm.nih.gov/pubmed/31857576
http://dx.doi.org/10.1038/s41467-019-13433-6

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