Cargando…

The efficacy of ropivacaine and bupivacaine in the caesarean section and the effect on the vital signs and the hemodynamics of the lying-in women

OBJECTIVE: To investigate the efficacy of ropivacaine and bupivacaine in caesarean section and vital signs and the hemodynamics of the lying-in women. METHODS: A total of 480 lying-in women who were admitted to this hospital for treatment between December 2017 and June 2018 were enrolled into this s...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Huaizhao, Gao, Qinghua, Xu, Ruixue, Dong, Wei, Zhang, Yanan, Fan, Jinxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923449/
https://www.ncbi.nlm.nih.gov/pubmed/31889783
http://dx.doi.org/10.1016/j.sjbs.2019.07.014
_version_ 1783481536248545280
author Wang, Huaizhao
Gao, Qinghua
Xu, Ruixue
Dong, Wei
Zhang, Yanan
Fan, Jinxin
author_facet Wang, Huaizhao
Gao, Qinghua
Xu, Ruixue
Dong, Wei
Zhang, Yanan
Fan, Jinxin
author_sort Wang, Huaizhao
collection PubMed
description OBJECTIVE: To investigate the efficacy of ropivacaine and bupivacaine in caesarean section and vital signs and the hemodynamics of the lying-in women. METHODS: A total of 480 lying-in women who were admitted to this hospital for treatment between December 2017 and June 2018 were enrolled into this study as the subjects, which were divided into the experiment group and the control group, with 240 subjects in each group. In the experiment group, subjects received the local anesthesia by infusion of 1.5 mL ropivacaine (0.75%), while those in the control group also took the local anesthesia by infusion of 1.5 mL bupivacaine (0.75%). Thereafter, we observed the differences in the anesthetic efficiency, vital signs and hemodynamics of the lying-in women between two groups. RESULTS: The excellent and good rates of the anesthesia in two groups were 92.1% and 87.9%, showing no obvious difference; in the experiment group, the average arterial pressures and systolic pressures at 5 min and 10 min after combined spinal and epidural analgesia (CSEA) were all elevated when comparing to the control group (all P < 0.05); in the experiment group, the onset time was obviously extended, while duration of sensory and motor block and the duration of motor block were all shorter than those in the control group (all P < 0.05). During anesthesia, the incidence rate of the adverse reactions in the control group was 2.50%, significantly higher than 0.83% in the experiment group (P < 0.05). CONCLUSION: Despite that ropivacaine and bupivacaine are efficient in anesthesia in the CSEA in the caesarean section, ropivacaine is more recommended for little influence on the hemodynamics, shorter duration of sensory block and motor block and low incidence rate of adverse reactions, which are conducive to the recovery and also safe to the patients.
format Online
Article
Text
id pubmed-6923449
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-69234492019-12-30 The efficacy of ropivacaine and bupivacaine in the caesarean section and the effect on the vital signs and the hemodynamics of the lying-in women Wang, Huaizhao Gao, Qinghua Xu, Ruixue Dong, Wei Zhang, Yanan Fan, Jinxin Saudi J Biol Sci Article OBJECTIVE: To investigate the efficacy of ropivacaine and bupivacaine in caesarean section and vital signs and the hemodynamics of the lying-in women. METHODS: A total of 480 lying-in women who were admitted to this hospital for treatment between December 2017 and June 2018 were enrolled into this study as the subjects, which were divided into the experiment group and the control group, with 240 subjects in each group. In the experiment group, subjects received the local anesthesia by infusion of 1.5 mL ropivacaine (0.75%), while those in the control group also took the local anesthesia by infusion of 1.5 mL bupivacaine (0.75%). Thereafter, we observed the differences in the anesthetic efficiency, vital signs and hemodynamics of the lying-in women between two groups. RESULTS: The excellent and good rates of the anesthesia in two groups were 92.1% and 87.9%, showing no obvious difference; in the experiment group, the average arterial pressures and systolic pressures at 5 min and 10 min after combined spinal and epidural analgesia (CSEA) were all elevated when comparing to the control group (all P < 0.05); in the experiment group, the onset time was obviously extended, while duration of sensory and motor block and the duration of motor block were all shorter than those in the control group (all P < 0.05). During anesthesia, the incidence rate of the adverse reactions in the control group was 2.50%, significantly higher than 0.83% in the experiment group (P < 0.05). CONCLUSION: Despite that ropivacaine and bupivacaine are efficient in anesthesia in the CSEA in the caesarean section, ropivacaine is more recommended for little influence on the hemodynamics, shorter duration of sensory block and motor block and low incidence rate of adverse reactions, which are conducive to the recovery and also safe to the patients. Elsevier 2019-12 2019-08-01 /pmc/articles/PMC6923449/ /pubmed/31889783 http://dx.doi.org/10.1016/j.sjbs.2019.07.014 Text en © 2019 Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Wang, Huaizhao
Gao, Qinghua
Xu, Ruixue
Dong, Wei
Zhang, Yanan
Fan, Jinxin
The efficacy of ropivacaine and bupivacaine in the caesarean section and the effect on the vital signs and the hemodynamics of the lying-in women
title The efficacy of ropivacaine and bupivacaine in the caesarean section and the effect on the vital signs and the hemodynamics of the lying-in women
title_full The efficacy of ropivacaine and bupivacaine in the caesarean section and the effect on the vital signs and the hemodynamics of the lying-in women
title_fullStr The efficacy of ropivacaine and bupivacaine in the caesarean section and the effect on the vital signs and the hemodynamics of the lying-in women
title_full_unstemmed The efficacy of ropivacaine and bupivacaine in the caesarean section and the effect on the vital signs and the hemodynamics of the lying-in women
title_short The efficacy of ropivacaine and bupivacaine in the caesarean section and the effect on the vital signs and the hemodynamics of the lying-in women
title_sort efficacy of ropivacaine and bupivacaine in the caesarean section and the effect on the vital signs and the hemodynamics of the lying-in women
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923449/
https://www.ncbi.nlm.nih.gov/pubmed/31889783
http://dx.doi.org/10.1016/j.sjbs.2019.07.014
work_keys_str_mv AT wanghuaizhao theefficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen
AT gaoqinghua theefficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen
AT xuruixue theefficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen
AT dongwei theefficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen
AT zhangyanan theefficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen
AT fanjinxin theefficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen
AT wanghuaizhao efficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen
AT gaoqinghua efficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen
AT xuruixue efficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen
AT dongwei efficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen
AT zhangyanan efficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen
AT fanjinxin efficacyofropivacaineandbupivacaineinthecaesareansectionandtheeffectonthevitalsignsandthehemodynamicsofthelyinginwomen