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Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells

Adoptive transfer of autologous polyclonal regulatory T cells (Tregs) is a promising option for reducing graft rejection in allogeneic transplantation. To gain therapeutic levels of Tregs there is a need to expand obtained cells ex vivo, usually in the presence of the mTOR inhibitor Rapamycin due to...

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Detalles Bibliográficos
Autores principales: Bergström, Marcus, Müller, Malin, Karlsson, Marie, Scholz, Hanne, Vethe, Nils Tore, Korsgren, Olle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923545/
https://www.ncbi.nlm.nih.gov/pubmed/31512504
http://dx.doi.org/10.1177/0963689719872488

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