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Hyaluronic acid-bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome, and immune responses in colitis.
While conventional approaches for inflammatory bowel diseases (IBD) mainly focus on suppressing hyperactive immune responses, it remains unclear how to address disrupted intestinal barriers, dysbiosis of the gut commensal microbiota, and dysregulated mucosal immune responses in IBD. Moreover, immuno...
Autores principales: | Lee, Yonghyun, Sugihara, Kohei, Gillilland, Merritt G., Jon, Sangyong, Kamada, Nobuhiko, Moon, James J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923573/ https://www.ncbi.nlm.nih.gov/pubmed/31427744 http://dx.doi.org/10.1038/s41563-019-0462-9 |
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