A simplified system for the effective expression and delivery of functional mature microRNAs in mammalian cells

MicroRNAs (miRNAs) are ~22 nucleotide noncoding RNAs that are involved in virtually all aspects of cellular process as their deregulations are associated with many pathological conditions. Mature miRNAs (mMIRs) are generated through a series of tightly-regulated nuclear and cytoplasmic processing ev...

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Detalles Bibliográficos
Autores principales: Fan, Jiaming, Feng, Yixiao, Zhang, Ruyi, Zhang, Wenwen, Shu, Yi, Zeng, Zongyue, Huang, Shifeng, Zhang, Linghuan, Huang, Bo, Wu, Di, Zhang, Bo, Wang, Xi, Lei, Yan, Ye, Zhenyu, Zhao, Ling, Cao, Daigui, Yang, Lijuan, Chen, Xian, Liu, Bin, Wagstaff, William, He, Fang, Wu, Xiaoxing, Zhang, Jing, Moriatis Wolf, Jennifer, Lee, Michael J., Haydon, Rex C., Luu, Hue H., Huang, Ailong, He, Tong-Chuan, Yan, Shujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923634/
https://www.ncbi.nlm.nih.gov/pubmed/31222181
http://dx.doi.org/10.1038/s41417-019-0113-y

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