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TNF-α Directly Enhances Osteocyte RANKL Expression and Promotes Osteoclast Formation
Osteoimmunology peeks into the interaction of bone and the immune system, which has largely proved to be a multiplex reaction. Osteocytes have been shown to regulate bone resorption through the expression of RANKL in physiologic and pathologic conditions. TNF-α, a product of the immune system, is an...
Autores principales: | Marahleh, Aseel, Kitaura, Hideki, Ohori, Fumitoshi, Kishikawa, Akiko, Ogawa, Saika, Shen, Wei-Ren, Qi, Jiawei, Noguchi, Takahiro, Nara, Yasuhiko, Mizoguchi, Itaru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923682/ https://www.ncbi.nlm.nih.gov/pubmed/31921183 http://dx.doi.org/10.3389/fimmu.2019.02925 |
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