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mTORC1 as a Regulator of Mitochondrial Functions and a Therapeutic Target in Cancer

Continuous proliferation of tumor cells requires constant adaptations of energy metabolism to rapidly fuel cell growth and division. This energetic adaptation often comprises deregulated glucose uptake and lactate production in the presence of oxygen, a process known as the “Warburg effect.” For man...

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Detalles Bibliográficos
Autores principales: de la Cruz López, Karen Griselda, Toledo Guzmán, Mariel Esperanza, Sánchez, Elizabeth Ortiz, García Carrancá, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923780/
https://www.ncbi.nlm.nih.gov/pubmed/31921637
http://dx.doi.org/10.3389/fonc.2019.01373

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