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mTORC1 as a Regulator of Mitochondrial Functions and a Therapeutic Target in Cancer
Continuous proliferation of tumor cells requires constant adaptations of energy metabolism to rapidly fuel cell growth and division. This energetic adaptation often comprises deregulated glucose uptake and lactate production in the presence of oxygen, a process known as the “Warburg effect.” For man...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923780/ https://www.ncbi.nlm.nih.gov/pubmed/31921637 http://dx.doi.org/10.3389/fonc.2019.01373 |