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Chondroitinase ABC reduces dopaminergic nigral cell death and striatal terminal loss in a 6-hydroxydopamine partial lesion mouse model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is characterised by dopaminergic cell loss within the substantia nigra pars compacta (SNc) that leads to reduced striatal dopamine content and resulting motor deficits. Identifying new strategies to protect these cells from degeneration and retain striatal dopami...

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Detalles Bibliográficos
Autores principales:	Fletcher, Edward J. R., Moon, Lawrence D. F., Duty, Susan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923832/ https://www.ncbi.nlm.nih.gov/pubmed/31862005 http://dx.doi.org/10.1186/s12868-019-0543-3

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