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DeepShape: estimating isoform-level ribosome abundance and distribution with Ribo-seq data
BACKGROUND: Ribosome profiling brings insight to the process of translation. A basic step in profile construction at transcript level is to map Ribo-seq data to transcripts, and then assign a huge number of multiple-mapped reads to similar isoforms. Existing methods either discard the multiple mappe...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923924/ https://www.ncbi.nlm.nih.gov/pubmed/31861979 http://dx.doi.org/10.1186/s12859-019-3244-0 |