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High-throughput sequencing of CD4(+) T cell repertoire reveals disease-specific signatures in IgG4-related disease
BACKGROUND: CD4(+) T cells play critical roles in the pathogenesis of IgG4-related disease (IgG4-RD). The aim of this study was to investigate the TCR repertoire of peripheral blood CD4(+) T cells in IgG4-RD. METHODS: The peripheral blood was collected from six healthy controls and eight IgG4-RD pat...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923942/ https://www.ncbi.nlm.nih.gov/pubmed/31856905 http://dx.doi.org/10.1186/s13075-019-2069-6 |