High-throughput sequencing of CD4(+) T cell repertoire reveals disease-specific signatures in IgG4-related disease

BACKGROUND: CD4(+) T cells play critical roles in the pathogenesis of IgG4-related disease (IgG4-RD). The aim of this study was to investigate the TCR repertoire of peripheral blood CD4(+) T cells in IgG4-RD. METHODS: The peripheral blood was collected from six healthy controls and eight IgG4-RD pat...

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Detalles Bibliográficos
Autores principales: Wang, Liwen, Zhang, Panpan, Li, Jieqiong, Lu, Hui, Peng, Linyi, Ling, Jing, Zhang, Xuan, Zeng, Xiaofeng, Zhao, Yan, Zhang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923942/
https://www.ncbi.nlm.nih.gov/pubmed/31856905
http://dx.doi.org/10.1186/s13075-019-2069-6

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