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EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV-1-infected individuals, irrespective of clinical statuses

BACKGROUND: EOS plays an important role in maintaining the suppressive function of regulatory T cells (Tregs), and induces a regulated transformation of Tregs into T helper-like cells, which are capable of secreting proinflammatory cytokines in response to specific inflammatory signals. Meanwhile, s...

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Detalles Bibliográficos
Autores principales:	Naito, Tadasuke, Ushirogawa, Hiroshi, Fukushima, Takuya, Tanaka, Yuetsu, Saito, Mineki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923961/ https://www.ncbi.nlm.nih.gov/pubmed/31856855 http://dx.doi.org/10.1186/s12985-019-1270-1

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