Excitotoxic glutamate causes neuronal insulin resistance by inhibiting insulin receptor/Akt/mTOR pathway

AIM: An impaired biological response to insulin in the brain, known as central insulin resistance, was identified during stroke and traumatic brain injury, for which glutamate excitotoxicity is a common pathogenic factor. The exact molecular link between excitotoxicity and central insulin resistance...

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Detalles Bibliográficos
Autores principales: Pomytkin, Igor, Krasil’nikova, Irina, Bakaeva, Zanda, Surin, Alexander, Pinelis, Vsevolod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Micro Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923972/
https://www.ncbi.nlm.nih.gov/pubmed/31856878
http://dx.doi.org/10.1186/s13041-019-0533-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923972/
https://www.ncbi.nlm.nih.gov/pubmed/31856878
http://dx.doi.org/10.1186/s13041-019-0533-5

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