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High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island
BACKGROUND: In recent years, the Asian tiger mosquito Aedes albopictus has emerged as a species of major medical concern following its global expansion and involvement in many arbovirus outbreaks. On Réunion Island, Ae. albopictus was responsible for a large chikungunya outbreak in 2005–2006 and mor...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924041/ https://www.ncbi.nlm.nih.gov/pubmed/31856896 http://dx.doi.org/10.1186/s13071-019-3840-x |
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author | Latreille, Anne C. Milesi, Pascal Magalon, Hélène Mavingui, Patrick Atyame, Célestine M. |
author_facet | Latreille, Anne C. Milesi, Pascal Magalon, Hélène Mavingui, Patrick Atyame, Célestine M. |
author_sort | Latreille, Anne C. |
collection | PubMed |
description | BACKGROUND: In recent years, the Asian tiger mosquito Aedes albopictus has emerged as a species of major medical concern following its global expansion and involvement in many arbovirus outbreaks. On Réunion Island, Ae. albopictus was responsible for a large chikungunya outbreak in 2005–2006 and more recently an epidemic of dengue which began at the end of 2017 and is still ongoing at the time of writing. This dengue epidemic has seen a high number of human cases in south and west coastal regions, while few cases have been reported in the north and east of the island. To better understand the role of mosquito populations in such spatial patterns of dengue virus transmission in Réunion Island, we examined the genetic diversity and population structure of Ae. albopictus sampled across the island. RESULTS: Between November 2016 and March 2017, a total of 564 mosquitoes were collected from 19 locations in three main climatic regions (West, East and Center) of Réunion Island and were genotyped using 16 microsatellite loci. A high genetic diversity was observed with 2–15 alleles per locus and the average number of alleles per population varying between 4.70–5.90. Almost all F(IS) values were significantly positive and correlated to individual relatedness within populations using a hierarchical clustering approach based on principal components analyses (HCPC). However, the largest part of genetic variance was among individuals within populations (97%) while only 3% of genetic variance was observed among populations within regions. Therefore, no distinguishable population structure or isolation by distance was evidenced, suggesting high rates of gene flow at the island scale. CONCLUSIONS: Our results show high genetic diversity but no genetic structure of Ae. albopictus populations in Réunion Island thus reflecting frequent movements of mosquitoes between populations probably due to human activity. These data should help in the understanding of Ae. albopictus vector capacity and the design of effective mosquito control strategies. |
format | Online Article Text |
id | pubmed-6924041 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-69240412019-12-30 High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island Latreille, Anne C. Milesi, Pascal Magalon, Hélène Mavingui, Patrick Atyame, Célestine M. Parasit Vectors Research BACKGROUND: In recent years, the Asian tiger mosquito Aedes albopictus has emerged as a species of major medical concern following its global expansion and involvement in many arbovirus outbreaks. On Réunion Island, Ae. albopictus was responsible for a large chikungunya outbreak in 2005–2006 and more recently an epidemic of dengue which began at the end of 2017 and is still ongoing at the time of writing. This dengue epidemic has seen a high number of human cases in south and west coastal regions, while few cases have been reported in the north and east of the island. To better understand the role of mosquito populations in such spatial patterns of dengue virus transmission in Réunion Island, we examined the genetic diversity and population structure of Ae. albopictus sampled across the island. RESULTS: Between November 2016 and March 2017, a total of 564 mosquitoes were collected from 19 locations in three main climatic regions (West, East and Center) of Réunion Island and were genotyped using 16 microsatellite loci. A high genetic diversity was observed with 2–15 alleles per locus and the average number of alleles per population varying between 4.70–5.90. Almost all F(IS) values were significantly positive and correlated to individual relatedness within populations using a hierarchical clustering approach based on principal components analyses (HCPC). However, the largest part of genetic variance was among individuals within populations (97%) while only 3% of genetic variance was observed among populations within regions. Therefore, no distinguishable population structure or isolation by distance was evidenced, suggesting high rates of gene flow at the island scale. CONCLUSIONS: Our results show high genetic diversity but no genetic structure of Ae. albopictus populations in Réunion Island thus reflecting frequent movements of mosquitoes between populations probably due to human activity. These data should help in the understanding of Ae. albopictus vector capacity and the design of effective mosquito control strategies. BioMed Central 2019-12-19 /pmc/articles/PMC6924041/ /pubmed/31856896 http://dx.doi.org/10.1186/s13071-019-3840-x Text en © The Author(s) 2019 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Latreille, Anne C. Milesi, Pascal Magalon, Hélène Mavingui, Patrick Atyame, Célestine M. High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island |
title | High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island |
title_full | High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island |
title_fullStr | High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island |
title_full_unstemmed | High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island |
title_short | High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island |
title_sort | high genetic diversity but no geographical structure of aedes albopictus populations in réunion island |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924041/ https://www.ncbi.nlm.nih.gov/pubmed/31856896 http://dx.doi.org/10.1186/s13071-019-3840-x |
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