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Prevalence of oral lesions in tuberculosis: A cross sectional study

OBJECTIVE: Tuberculosis (Tb) is a fatal infectious disease that primarily affects the pulmonary system and rarely occurs in other body organs including oral cavity. The aim of this study was to report all patients with primary manifestations of oral tuberculosis and to evaluate the clinical characte...

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Autores principales: Rout, Purnendu, Modipalle, Varsha, Hedge, Shruthi S, Patel, Nirav, Uppala, Sravani, Shetty, Prajwal K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924226/
https://www.ncbi.nlm.nih.gov/pubmed/31879619
http://dx.doi.org/10.4103/jfmpc.jfmpc_714_19
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author Rout, Purnendu
Modipalle, Varsha
Hedge, Shruthi S
Patel, Nirav
Uppala, Sravani
Shetty, Prajwal K
author_facet Rout, Purnendu
Modipalle, Varsha
Hedge, Shruthi S
Patel, Nirav
Uppala, Sravani
Shetty, Prajwal K
author_sort Rout, Purnendu
collection PubMed
description OBJECTIVE: Tuberculosis (Tb) is a fatal infectious disease that primarily affects the pulmonary system and rarely occurs in other body organs including oral cavity. The aim of this study was to report all patients with primary manifestations of oral tuberculosis and to evaluate the clinical characteristics of oral tuberculosis lesions. All these patients were subsequently diagnosed with tuberculosis based on oral histological findings and referred for management and therapy. MATERIALS AND METHODS: Twelve patients with oral lesions from the year 2010 to 2018 were histologically diagnosed as having tuberculosis, who did not give any history of the disease, following surgical biopsy. Clinical symptoms, auxiliary examinations, treatments, and outcomes were recorded and analyzed. RESULTS: Oral TB was found in all 12 patients; 8 males and 4 females, with male to female ratio 8:4. Involved oral sites included the angle of the mandible (one case), right mandibular molar region (two cases), left mandibular molar region (four cases), gingiva (three cases), buccal mucosa (one case), and the tongue (one case). Oral TB patients in this series ranged in the age group of 6–65 years. All the lesions were suggestive of primary tuberculosis. The appearance of the affected mucosa in oral TB was variable. The most common manifestation was ulceration and swelling of the mucosa. CONCLUSION: TB should be considered in patients with oral ulcerations and swellings. A biopsy specimen for histological study, acid-fast stains, and cultures should be obtained for confirmation and differential diagnosis along with other conditions.
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spelling pubmed-69242262019-12-26 Prevalence of oral lesions in tuberculosis: A cross sectional study Rout, Purnendu Modipalle, Varsha Hedge, Shruthi S Patel, Nirav Uppala, Sravani Shetty, Prajwal K J Family Med Prim Care Original Article OBJECTIVE: Tuberculosis (Tb) is a fatal infectious disease that primarily affects the pulmonary system and rarely occurs in other body organs including oral cavity. The aim of this study was to report all patients with primary manifestations of oral tuberculosis and to evaluate the clinical characteristics of oral tuberculosis lesions. All these patients were subsequently diagnosed with tuberculosis based on oral histological findings and referred for management and therapy. MATERIALS AND METHODS: Twelve patients with oral lesions from the year 2010 to 2018 were histologically diagnosed as having tuberculosis, who did not give any history of the disease, following surgical biopsy. Clinical symptoms, auxiliary examinations, treatments, and outcomes were recorded and analyzed. RESULTS: Oral TB was found in all 12 patients; 8 males and 4 females, with male to female ratio 8:4. Involved oral sites included the angle of the mandible (one case), right mandibular molar region (two cases), left mandibular molar region (four cases), gingiva (three cases), buccal mucosa (one case), and the tongue (one case). Oral TB patients in this series ranged in the age group of 6–65 years. All the lesions were suggestive of primary tuberculosis. The appearance of the affected mucosa in oral TB was variable. The most common manifestation was ulceration and swelling of the mucosa. CONCLUSION: TB should be considered in patients with oral ulcerations and swellings. A biopsy specimen for histological study, acid-fast stains, and cultures should be obtained for confirmation and differential diagnosis along with other conditions. Wolters Kluwer - Medknow 2019-12-10 /pmc/articles/PMC6924226/ /pubmed/31879619 http://dx.doi.org/10.4103/jfmpc.jfmpc_714_19 Text en Copyright: © 2019 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Rout, Purnendu
Modipalle, Varsha
Hedge, Shruthi S
Patel, Nirav
Uppala, Sravani
Shetty, Prajwal K
Prevalence of oral lesions in tuberculosis: A cross sectional study
title Prevalence of oral lesions in tuberculosis: A cross sectional study
title_full Prevalence of oral lesions in tuberculosis: A cross sectional study
title_fullStr Prevalence of oral lesions in tuberculosis: A cross sectional study
title_full_unstemmed Prevalence of oral lesions in tuberculosis: A cross sectional study
title_short Prevalence of oral lesions in tuberculosis: A cross sectional study
title_sort prevalence of oral lesions in tuberculosis: a cross sectional study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924226/
https://www.ncbi.nlm.nih.gov/pubmed/31879619
http://dx.doi.org/10.4103/jfmpc.jfmpc_714_19
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