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Team COUNCIL OF RICKS submission for EUPA YPIC 2017

Using primarily LC-MS/MS de novo sequencing techniques, we concluded that the peptides form the following sentence from Sir JJ Thomson’s preface to Rays of Positive Electricity and Their Application to Chemical Analyses: “I feel sure that there are many problems in chemistry which could be solved wi...

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Detalles Bibliográficos
Autores principales: Pino, Lindsay K., Searle, Brian C, Yang, Han-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924282/
https://www.ncbi.nlm.nih.gov/pubmed/31890550
http://dx.doi.org/10.1016/j.euprot.2019.07.009
Descripción
Sumario:Using primarily LC-MS/MS de novo sequencing techniques, we concluded that the peptides form the following sentence from Sir JJ Thomson’s preface to Rays of Positive Electricity and Their Application to Chemical Analyses: “I feel sure that there are many problems in chemistry which could be solved with far greater ease by this than by any other method. The method is surprisingly sensitive, more so even than that of spectrum analysis, requires an infinitesimal amount of material, and does not require this to be specially purified.” Here, we detail our process for deciphering the peptide mixture composition and finding the sentence they form and from what book the sentence comes from.