Cargando…
Natural Killer Cell Hypo-responsiveness in Chronic Lymphocytic Leukemia can be Circumvented In Vitro by Adequate Activating Signaling
Chronic lymphocytic leukemia (CLL) is characterized by an acquired immune dysfunction, which may underlie the hampered efficacy of cellular immunotherapy. Most data on dampened immune responses in CLL come from studies investigating CLL and T cell interactions. Natural killer (NK) cells may be an at...
Autores principales: | Hofland, Tom, Endstra, Sanne, Gomes, Calum K.P., de Boer, Renate, de Weerdt, Iris, Bobkov, Vladimir, Riedl, Jurgen A., Heukers, Raimond, Smit, Martine J., Eldering, Eric, Levin, Mark-David, Kater, Arnon P., Tonino, Sanne H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924557/ https://www.ncbi.nlm.nih.gov/pubmed/31976482 http://dx.doi.org/10.1097/HS9.0000000000000308 |
Ejemplares similares
-
Engaging Cytotoxic T and NK Cells for Immunotherapy in Chronic Lymphocytic Leukemia
por: Hofland, Tom, et al.
Publicado: (2019) -
Functional Differences Between EBV- and CMV-Specific CD8(+) T cells Demonstrate Heterogeneity of T cell Dysfunction in CLL
por: Hofland, Tom, et al.
Publicado: (2020) -
Human CXCR5(+)PD‐1(+) CD8 T cells in healthy individuals and patients with hematologic malignancies
por: Hofland, Tom, et al.
Publicado: (2020) -
Combining novel agents in chronic lymphocytic leukemia: Greater than the sum of its parts?
por: de Weerdt, Iris, et al.
Publicado: (2019) -
Overcoming the Hurdles of Autologous T-Cell-Based Therapies in B-Cell Non-Hodgkin Lymphoma
por: van Bruggen, Jaco A. C., et al.
Publicado: (2020)