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CDK4/6 Inhibitor Palbociclib Amplifies the Radiosensitivity to Nasopharyngeal Carcinoma Cells via Mediating Apoptosis and Suppressing DNA Damage Repair

BACKGROUND: Radiotherapy is the primary approach for nasopharyngeal carcinoma (NPC). Although high survival rates can be obtained with radiation for early stage lesions, distant metastasis and local recurrence frequently occur. In this study, we pioneeringly investigated the antitumor activity and u...

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Detalles Bibliográficos
Autores principales: Xie, Xianhe, Zheng, Weili, Chen, Ting, Lin, Wanzun, Liao, Ziyuan, Liu, Junjin, Ding, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924590/
https://www.ncbi.nlm.nih.gov/pubmed/31908479
http://dx.doi.org/10.2147/OTT.S234221