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Concomitant intraperitoneal and systemic chemotherapy for extensive peritoneal metastases of colorectal origin: protocol of the multicentre, open-label, phase I, dose-escalation INTERACT trial
INTRODUCTION: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) has become standard of care for patients with peritoneal metastases of colorectal origin with a low/moderate abdominal disease load. In case of a peritoneal cancer index (PCI) score >20, CRS-HIPEC is not...
Autores principales: | de Boer, Nadine Leonie, Brandt-Kerkhof, Alexandra R M, Madsen, Eva V E, Diepeveen, Marjolein, van Meerten, Esther, van Eerden, Ruben A G, de Man, Femke M, Bouamar, Rachida, Koolen, Stijn L W, de Hingh, Ignace H J T, Bakkers, Checca, Rovers, Koen P, Creemers, Geert-Jan M, Deenen, Maarten J, Kranenburg, Onno W, Constantinides, Alexander, Mathijssen, Ron H J, Verhoef, Cornelis, Burger, Jacobus W A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924694/ https://www.ncbi.nlm.nih.gov/pubmed/31818845 http://dx.doi.org/10.1136/bmjopen-2019-034508 |
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