Cargando…
Influence of leftover antibiotics on self-medication with antibiotics for children: a cross-sectional study from three Chinese provinces
OBJECTIVES: To investigate leftover antibiotics and their influence on self-medication with antibiotics (SMA) for Chinese children, and further explore the different influences of leftovers from two main sources: previous prescriptions and pharmaceutical purchases. DESIGN: A cross-sectional question...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924767/ https://www.ncbi.nlm.nih.gov/pubmed/31843850 http://dx.doi.org/10.1136/bmjopen-2019-033679 |
_version_ | 1783481784467456000 |
---|---|
author | Sun, Chenhui Hu, Yanhong Jessika Wang, Xiaomin Lu, Jingjing Lin, Leesa Zhou, Xudong |
author_facet | Sun, Chenhui Hu, Yanhong Jessika Wang, Xiaomin Lu, Jingjing Lin, Leesa Zhou, Xudong |
author_sort | Sun, Chenhui |
collection | PubMed |
description | OBJECTIVES: To investigate leftover antibiotics and their influence on self-medication with antibiotics (SMA) for Chinese children, and further explore the different influences of leftovers from two main sources: previous prescriptions and pharmaceutical purchases. DESIGN: A cross-sectional questionnaire study. SETTING: The participants were approached through kindergartens and primary schools as well as in vaccination clinics. PARTICIPANTS: A total of 9526 parents from three Chinese provinces whose children were aged 0–13 years completed the survey. OUTCOME MEASURES: The prevalence of keeping antibiotics at home for children and the proportion of leftover antibiotics from two main sources were measured by a self-administrated questionnaire. Logistic regression models were established to examine the association between keeping antibiotics at home and SMA for children, specifically the risks of leftovers from two main sources. RESULTS: Overall, 4580 (48.1%) reported keeping antibiotics at home for children. Among those who had leftovers, 2891 (63.1%) reported that their leftovers came from previous prescriptions and 1619 (35.3%) reported that their leftovers came from pharmaceutical purchases. Mothers, older age of child, higher household income, higher education level and medical background were significantly associated with keeping antibiotics at home. Keeping antibiotics at home was significantly associated with SMA for children (adjusted OR=4.91, 95% CI 3.84 to 6.28). Particularly, compared with parents who did not keep antibiotics at home, parents who kept leftover antibiotics from previous prescriptions and those whose leftovers came from pharmaceutical purchases were 3.80 (95% CI 2.89 to 5.00) and 6.45 (95% CI 4.89 to 8.51) times more likely to engage in SMA for children, respectively. CONCLUSIONS: Keeping antibiotics at home for children was pervasive in China. Most leftovers came from previous prescriptions, while those from pharmacies had a higher risk of SMA for children. |
format | Online Article Text |
id | pubmed-6924767 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-69247672020-01-02 Influence of leftover antibiotics on self-medication with antibiotics for children: a cross-sectional study from three Chinese provinces Sun, Chenhui Hu, Yanhong Jessika Wang, Xiaomin Lu, Jingjing Lin, Leesa Zhou, Xudong BMJ Open Paediatrics OBJECTIVES: To investigate leftover antibiotics and their influence on self-medication with antibiotics (SMA) for Chinese children, and further explore the different influences of leftovers from two main sources: previous prescriptions and pharmaceutical purchases. DESIGN: A cross-sectional questionnaire study. SETTING: The participants were approached through kindergartens and primary schools as well as in vaccination clinics. PARTICIPANTS: A total of 9526 parents from three Chinese provinces whose children were aged 0–13 years completed the survey. OUTCOME MEASURES: The prevalence of keeping antibiotics at home for children and the proportion of leftover antibiotics from two main sources were measured by a self-administrated questionnaire. Logistic regression models were established to examine the association between keeping antibiotics at home and SMA for children, specifically the risks of leftovers from two main sources. RESULTS: Overall, 4580 (48.1%) reported keeping antibiotics at home for children. Among those who had leftovers, 2891 (63.1%) reported that their leftovers came from previous prescriptions and 1619 (35.3%) reported that their leftovers came from pharmaceutical purchases. Mothers, older age of child, higher household income, higher education level and medical background were significantly associated with keeping antibiotics at home. Keeping antibiotics at home was significantly associated with SMA for children (adjusted OR=4.91, 95% CI 3.84 to 6.28). Particularly, compared with parents who did not keep antibiotics at home, parents who kept leftover antibiotics from previous prescriptions and those whose leftovers came from pharmaceutical purchases were 3.80 (95% CI 2.89 to 5.00) and 6.45 (95% CI 4.89 to 8.51) times more likely to engage in SMA for children, respectively. CONCLUSIONS: Keeping antibiotics at home for children was pervasive in China. Most leftovers came from previous prescriptions, while those from pharmacies had a higher risk of SMA for children. BMJ Publishing Group 2019-12-15 /pmc/articles/PMC6924767/ /pubmed/31843850 http://dx.doi.org/10.1136/bmjopen-2019-033679 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Paediatrics Sun, Chenhui Hu, Yanhong Jessika Wang, Xiaomin Lu, Jingjing Lin, Leesa Zhou, Xudong Influence of leftover antibiotics on self-medication with antibiotics for children: a cross-sectional study from three Chinese provinces |
title | Influence of leftover antibiotics on self-medication with antibiotics for children: a cross-sectional study from three Chinese provinces |
title_full | Influence of leftover antibiotics on self-medication with antibiotics for children: a cross-sectional study from three Chinese provinces |
title_fullStr | Influence of leftover antibiotics on self-medication with antibiotics for children: a cross-sectional study from three Chinese provinces |
title_full_unstemmed | Influence of leftover antibiotics on self-medication with antibiotics for children: a cross-sectional study from three Chinese provinces |
title_short | Influence of leftover antibiotics on self-medication with antibiotics for children: a cross-sectional study from three Chinese provinces |
title_sort | influence of leftover antibiotics on self-medication with antibiotics for children: a cross-sectional study from three chinese provinces |
topic | Paediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924767/ https://www.ncbi.nlm.nih.gov/pubmed/31843850 http://dx.doi.org/10.1136/bmjopen-2019-033679 |
work_keys_str_mv | AT sunchenhui influenceofleftoverantibioticsonselfmedicationwithantibioticsforchildrenacrosssectionalstudyfromthreechineseprovinces AT huyanhongjessika influenceofleftoverantibioticsonselfmedicationwithantibioticsforchildrenacrosssectionalstudyfromthreechineseprovinces AT wangxiaomin influenceofleftoverantibioticsonselfmedicationwithantibioticsforchildrenacrosssectionalstudyfromthreechineseprovinces AT lujingjing influenceofleftoverantibioticsonselfmedicationwithantibioticsforchildrenacrosssectionalstudyfromthreechineseprovinces AT linleesa influenceofleftoverantibioticsonselfmedicationwithantibioticsforchildrenacrosssectionalstudyfromthreechineseprovinces AT zhouxudong influenceofleftoverantibioticsonselfmedicationwithantibioticsforchildrenacrosssectionalstudyfromthreechineseprovinces |